Orochimaru has been one of Naruto’s biggest villains. He’s been around for a long time and kept coming back. That is, until Sasuke put him in his place. There was never any doubt that Sasuke would defeat Orochimaru. Orochimaru can’t defeat an Uchiha of Sasuke’s caliber.

Sasuke is the strongest being in all of media and cannot be defeated. He’s far too powerful for that. Orochimaru and Sasuke have been rivals ever since Orochimaru dared challenge him in the forest of death. Since then it has only been a matter of time until the fight was settles. Orochimaru takes a loss in this match. Sasuke wins.