Motoko Kusanagi is a skilled agent who is good with a gun. She has above average speed and strength which have served her well on the battlefield. That being said, Pyrrha is a Polarity master who is exceptional in combat. Motoko will quickly be overwhelmed by this fighter and since she is part metal that doesn’t bode well. Pyrrha would be able to rip her apart without even getting near Motoko. Pyrrha Nikos wins.