Suggested by Sonic Wario has his Wario Man form at the ready and he’s always been a pretty talented adventurer. I think Little Mac could give him a pretty reasonable fight and the match could actually be close. That being said, Wario would still claim the edge in the end. His ability to fly is a huge advantage in this battle as he isn’t limited to duking it out with Mac. This way Wario can fly and tackle his way to victory. Wario wins.