Suggested by iKnowledge Sam has a ton of experience dealing with high ranking demons. He was even able to resist Lucifer which is no small feat. Mephisto is about as high ranked as you can get for a demon though so you can’t even compare him to most. Mephisto has stood up to guys like Dr. Doom and Thanos in the past even if his results may not have been great. He certainly took a beating but his abilities are very real. I believe the sheer force of his energy projection abilities will be too much for Sam and will punch through his TK shield. Mephisto wins.