Sasuke is a pretty powerful fighter and has defeated many in the past. Broly has incredible strength and can destroy whole solar systems, but in the end it’s not enough to take down Sasuke. If Sasuke activates his Sharingan then he can take down Broly once and for all! Broly just needed to be faster. Sasuke wins.
Update 8 7 2020 Sasuke is incredibly fast, but he’s not going to be able to handle Broly. Broly wins.