Sakura has developed into a very powerful shinobi, but she won’t be able to defeat Kaguya. Kaguya makes her debut onto the blog at last and her abilities are not to be underestimated. Debatably, her physical abilities are on par with Sakura’s and her array of attacks is much larger. She should be able to evade Sakura’s blows while dealing out her own. A few minutes of such an onslaught should suffice. Kaguya wins.