Serpentor is a tricky GI Joe villain who actually managed to overthrow Cobra Commander. He shouldn’t be underestimated and while he has no super powers, he could certainly defeat Larry in a hand to hand battle. Larry doesn’t have the experience that Serpentor possesses and doesn’t seem all that athletic either. Serpentor will simply prove to be too much for good ole Larry. It’s been a tough road for Appleton, but he is nearing the end of his journey. Serpentor wins.