Suggested by Eric Annie Leonhart and Mikasa are both fairly adept at hand to hand combat and are fairly evenly matched. In a pure fist fight, I’d give Mikasa the edge though. What helps give Annie an edge is the fact that she has her Titan Mode abilities. Mikasa has been shown to take down Titans before, but Annie has the clear advantage with her hardening ability and the fact that she doesn’t lose her combat prowess. She will simply have too many abilities for a human, even one as skilled as Mikasa, to defeat. Annie Leonhart wins.