Suggested by Destroyer Mikasa is definitely a very solid fighter and she’s always been a pretty cool character. That being said, she isn’t quite ready to take on Samus. Both of them are basically superhuman in terms of physical ability, but Samus has the decisive advantage when you take into account her armor. With that she heavily outranks Mikasa in both power and speed. Samus also gets an incredible arsenal of projectiles that she can use to completely overwhelm the scout. Samus wins.