Suggested by Destroyer Little Mac is a good boxer and someone who can definitely hold his own in a fight. That being said, Master Chief has the overwhelming advantage in this fight. Mac isn’t a long range fighter, he needs Chief to get in close in order to deal any damage. That’s a huge weakness because all Master Chief has to do in order to claim victory…is not to approach. So long as he does that there really isn’t anything that Little Mac can do to win. His options are severely limited. Master Chief wins.