Suggested by Sonic Brainiac is one of Superman’s deadliest foes. While he isn’t really known as a physical fighter, he’s shown that he can go up against just about anyone in close quarters combat. Superman Prime is not one of those opponents though. Even in Brainiac’s golden mode I don’t see him lasting long here. Prime’s abilities are even greater than that of Superman’s which is already at a high level. Brainiac will be completely overwhelmed in speed and power. Superman Prime wins.