Suggested by Anonymous Isshiki Ōtsutsuki is back once again and this time he’s taking on an immortal fighter. Immortality is one of those abilities that is only good if it’s paired with instant regeneration. Otherwise it can be more of a curse than anything else. Fortuna doesn’t have any abilities that would allow her to deal damage to Isshiki and isn’t able to dodge him so she will only last as long as her immortality keeps her in the game. Once the energy is spent up she will be down for the count. Isshiki Ōtsutsuki wins.