This is a tribute to Dr. Strange and the Multiverse of Madness. Dr Strange looked pretty good here as he always had a plan and kept on fighting through to the end. A barrier will not be a big deal for him to get across and he definitely has the firepower to pull it off. The Harvester Queen is quite large but in this case that is a disadvantage as Dr Strange can just light her up with energy attacks and she will have no way to dodge. Dr Strange wins.