Suggested by Random Scorpion is a pretty strong Spiderman villain who is probably underratted. He can physically keep up with Spiderman and even surpasses him depending on the suit. Once he lands a hit on you the poison will do the rest. That being said, he’ll have a hard time landing a hit on Esdeath because of her speed as well as the large amount of ice that she always has at the ready. It will effectively block all of his incoming attacks and that will destroy any possible momentum that he may have had. Esdeath wins.