Suggested by Anonymous Isshiki Ōtsutsuki has already proven himself with quite a few wins. This one is naturally going to go in much the same way as Lucifer can’t really hope to take Isshiki down in a fair fight. Not only does this guy have the massive speed advantage but with one punch Isshiki should be able to take Lucifer down for the count. The guy just doesn’t have what it takes to defeat one of the premiere Boruto villains. Isshiki Ōtsutsuki wins.