Number 6 is one of the strongest Vigilante villains around. The guy has super strength, speed, regeneration, and a whole lot of other tricks at his disposal. The guy could take on most fighters but I would still give Deku the edge here. Deku has enough raw power where he should be able to get past Number 6’s regeneration. Additionally with 100% power Deku should be able to match his speed as well. It may be a difficult fight but it’s one that Deku should win. Deku wins.