Suggested by Destroyer Madame Hydra is a formidable fighter but for human level threats. She is definitely not someone you’d expect to take on a Kaiju and win. Space Godzilla’s stats are just way too far above hers. His sheer power would give him such an advantage that there would really be no coming back from that. Madame Hydra just wouldn’t stand a chance here and would quickly be taken down for the count. She would at least needs some kind of super gun to try and make a comeback. Space Godzilla wins.