Suggested by Destroyer Derpy can fly fast but she’s not ready for the Python. See, Pythons have turned large in several films over the years and a large one would be too much for Derpy. She has no powerful attack moves with which to counter the snake’s bites or quick lunges. That makes the match lopsided but not in her favor. Derpy really needs some kind of super energy attack in order to turn the tables and I’m not sure when that’ll ever happen. Python wins.