Snake Eyes has some pretty impressive speed and takes this round. Deadpool’s a tough fighter, but I’m not sure how he can hope to win this round. Ever since seeing Sigma 6, I’ve gained newfound respect for Snake Eyes and his abilities. Deadpool will be back someday. Snake Eyes wins.
DReager1.com 
Deadpool. Healing factor + teleport, he’s pretty much got the edge.
Those are certainly great edges, but I don’t think he can keep up with Snake Eyes speed even with the teleporting. In Sigma 6, Snake Eyes has incredible speed and also giant energy blasts from his gun. Not to mention that he has a Sigma Suit which increases his defense and attack power even more! He’s also mastered the legendary 3 slashes that merge into the ultimate sword technique. When Deadpool gets serious he’s also a deadly threat, but I think that he’s met his match
Doesn’t Deadpool get Mjolnir? And how does Snake Eyes deal with Deadpool’s regeneration?
Yes, Deadpool has Mjolnir and has access to his Hulk form (Pretty sure he got one) I just think the speed difference will be too great. Well, healing factors are definitely great, but if Snake Eyes splits him in half, the fight is basically over. Given time, he could get himself back together, but Snake Eyes won’t exactly let that happen. Eventually Deadpool would be no more.
Mjolnir AND Hulk form? Snake Eyes doesn’t stand a chance! Bear in mind, while Snake Eyes is fast, Deadpool isn’t exactly slow himself, and I doubt any of his attacks could be as strong as a blow from Mjolnir backed up by Hulk-like strength…
But I think Snake Eyes’s sword could pierce Deadpool, even in Hulk/Thor form. So, once he’s missing his arms, then the fight is pretty much set. Plus, I think Snake Eyes can still speedblitz Deadpool. Deadpool may be fast, but Snake Eyes is extremely fast! Plus he can spam his energy blasts