Ratchet is a genius mechanic and he has had quite a few game changing weapons in the past, but none of them are quite good enough to take Ms. M down for the count. To an extent she can block all of his energy attacks and Ratchet doesn’t have any guns fast enough to tag her. This is simply a mismatch where brains don’t take the win against brawn. It’ s just how it goes sometimes. Ms. Marvel wins.