Suggested by Destroyer Mr Game and Watch can shapeshift which is really handy and he definitely has some good fire torches but I don’t think he quite has the raw offensive power needed to beat Biollante. At the end of the day Biollante has the massive advantage thanks to the size difference and sheer durability. Mr Game and Watch doesn’t really have any options that would be strong enough to directly knock her out. Biollante wins.