Suggested by Destroyer J Jonah Jameson doesn’t usually fight all that much but he did get powers once during Spider Island. This included super strength, speed, and webbing which means that Howard is completely doomed here. There’s really not much that he can hope to do against a superhuman. Jonah is just out of Howard’s league here. He would be able to dodge any possible attack that Howard tries to launch at him. J Jonah Jameson wins.
Even without Jameson’s Spider Island powers, it’s not hopeless for either, if their aim is good enough, or their fists are skilled enough.
True, as long as you dodge Howard’s first punch then you’ve got a chance. Jameson definitely has a lot of gusto