Suggested by iKnowledge Ryu returns but Kabuto is an even more difficult match than Kisame. Kabuto’s speed was enough to keep up with both Itachi and Sasuke at the same time. There’s no way Ryu’s going to be hitting this guy and Kabuto’s regeneration will also come in handy here. Kabuto’s final form was pretty crazy that’s for sure. Ryu would likely have the edge here in any circumstance outside of the final arc where Kabuto’s power hit a whole new level. At that point he just becomes too fast. Kabuto wins.