Altair is a pretty good fighter and he would give Ezio a solid fight. They’re more or less equal in hand to hand combat, but I think that Ezio’s equipment is a little better. He has armors that will help to lesson the damage from Altair’s attacks and his fighting skills should do the rest. Of course Altair has the Armor of Altair which will provide him with a lot of defense as well. It’s definitely a close battle and it could have gone either way. Ezio wins.