Ruby (SHIELD) vs Ruby Rose

Ruby was certainly a powerful opponent in Agents of SHIELD. Her disc is quite sharp so a single hit can be fatal for any mortal. Fortunately Ruby has her aura to protect her from such attacks. Rose also has the edge in speed so good luck trying to land any hit on her. Ruby (SHIELD) will be out of options in the blink of an eye and will quickly be sliced and diced by Ruby Rose. Ruby Rose wins.