Suggested by Sonic Misty Knight and Coulson both have robotic arms but Misty’s is considerably more impressive. She can fire off energy blasts, destroy almost any metal, and her arm is just more versatile. Coulson has more weapons and tech at his disposal though so he would have the advantage in a prolonged battle. Misty is good at hand to hand combat too though so she should be able to rush in and dictate the terms of battle by forcing this into a close combat situation. Misty Knight wins.