Suggested by Sonic The Lizard is a pretty fierce fighter. His hand to hand skills are augmented by his strength and savagery in combat. That being said, Spiderwoman will be able to keep up. While I think she would likely lose in their base forms, she was possessed by the symbiote at one point which greatly augmented her abilities and she has also had upgrades to her electricity to zap Lizard from a distance I don’t see a path to victory for Lizard here. His final form does make this pretty close though and he has had various augmentations as well. This will definitely come down to the wire. Spiderwoman wins.