Suggested by Anonymous The Third Hokage is known as the professor since he knows so many Ninjutsu. He would have a lot of tricks in his arsenal but the problem is that they just wouldn’t do much of anything here. The power gap is too large and Isshiki can destroy him with a simple move from just about anywhere. Hiruzen would have no time to dodge. Isshiki Otsutsuki wins.
Isshiki Otsutsuki vs Hiruzen Sarutobi
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