Suggested by Sonic Lets put it this way, Mr Mxy is a guy who can mess with reality and knows how to throw a good punch but he’s not usually known as a big fighter. The reason for that is because he just isn’t the kind of guy who gets in close. You could say the same about Professor X but his experience is considerably more impressive and we have seen him show good battle tactics when he can walk. Mix that in with his Onslaught form and I don’t see Mr Mxy being able to win this one. Professor X wins.
Suggested by Sonic Mr Mxyzptlk is a fairly unpredictable Superman enemy who is always running around and causing trouble. His chaotic magic should not be underestimated since he can do a whole lot with it. He can activate his super form and also keep Orion guessing the whole time. That said, he has no real way to injure Orion so as soon as the guy lands a good shot that will be game over. Orion wins.
Suggested by Destroyer The BioLizard has returned and he has more than enough energy abilities to take on Mr Mxyzptlk. Mr Mxyzptlk mostly thrives around reality warping although the guy has shown that he does have the talent and ability to actually get into the ring to fight once in a while. He has your basic energy blast skills along with super strength, speed, and a few other such talents at his disposal. They just won’t be enough to get past a stream of lasers and barriers. The BioLizard wins.
Suggested by Sonic Solomon Grundy may not be one of my favorite DC villains but the guy does pack a real punch. When he returned in his zombie mode even Superman was having a hard time against him. I have no doubt that Mr Mxy would also be running at the end of his rope here. He has a lot of reality warping skills and some energy blasts but nothing that would really hurt this zombie. Try as he might, there’s no way for Mxy to stop him. Solomon Grundy wins.
Suggested by iKnowledge Mr Mxyzptlk is a tricky Superman villain who is always trying to make a mess of things. What he lacks in traditional fighting ability he makes up for with his reality altering abilities. That won’t be enough to defeat a master duelist like Kaiba though. Kaiba can harness the heart of the cards and summon forth his impressive Obelisk The Tormentor card. With that at his disposal defeat is not an option. A single hit should end the fight. Kaiba wins.
Suggested by iKnowledge Mr. Mxy may have a lot of tricks up his sleeve, but I wouldn’t count on him lasting very long against Goku. A single punch would be enough to take the guy out for the count but Goku could probably just power up to get the same effect. The Saiyan wouldn’t even need any of his Super Saiyan abilities to win here. All Mr. Mxy can do is cause a lot of chaos to at least try and buy some time. That’s his only viable tactic here. Goku wins.
Mr Mxyzptlk is back after being gone from the blog for a while. He’s not typically much of a fighter, but he did fight Superman seriously once during the “Whatever Happened To The Man of Tomorrow” story. We learned that he could easily defeat Larry since that form gave him super strength as well as a good amount of speed. Larry would simply be outmatched right from the start! Mr Mxyzptlk wins.
Mr Mxyzptlk is back, but he won’t be able to stop Deadpool! Deadpool has his healing factor and his guns at the ready. Mr Mxyzptlk will have a hard time trying to deal with all of that. He definitely likes making tricks, but Deadpool always manages to get the last laugh. Deadpool wins.
Update! As of 07/11/2016 It has been pointed out that Mr. Mxyzptlk aqctually has had some decent moments and feats in the comics with serious firepower. I don’t think Deadpool will be able to keep up with this guy. Mr. Mxyzptlk wins.
Mr Mxyzptlk is back, but this time he’s up against Lazerman. Needless to say…he’s doomed! Lazerman can fire beams of such raw power that not even Mr Mxyzptlk can take him down. Mr Mxyzptlk may be a tricky villain, but he’s just not on the same level as Lazerman. Lazerman takes another win. Lazerman wins.