Suggested by iknowledge Mephisto is a pretty powerful Marvel villain. He’s always lurking just behind the scenes waiting to throw the world into chaos. That being said, he won’t have an answer for Yugi’s army of monsters. There are too many of them for him to stop and they all have special abilities. If he tries to go past them and head straight for Yugi he will quickly be ambushed by a trap card. It’s a lose-lose situation for him either way. Yugi wins.